Simvastatin (Zocor) Drug Uses, Doses, Side Effects & Information | LowestMed

Simvastatin, Generic for Zocor

Simvastatin is a statin drug used to lower fats and “bad” cholesterols in the blood.

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Simvastatin is used for:

Simvastatin is used to reduce the chances of developing health issues such as stroke and heart disease that are partially caused by higher cholesterol levels. Doctors also prescribe Simvastatin to lower the risk of heart complications in certain people with diabetes, coronary heart disease, or other risk factors. It works to reduce the amount of cholesterol in the blood by blocking an enzyme that is needed to make cholesterol.

How to use Simvastatin:

Before using Simvastatin, be sure to consult your doctor and consider the risks of taking the medicine. This is a decision you and your doctor will make.

Consider the following before using Simvastatin:


Discuss any unusual or allergic reactions to Simvastatin, or any other medicines, with your doctor. You should also make your physician aware of any other allergies, such as food, allergies to dyes, preservatives, or animals.


Studies performed, to date, have not identified any pediatric-specific problems that would limit the usefulness of Simvastatin in children 10 to 17 years of age. Although, safety and efficacy have not been established in children younger than 10-years-old.


Studies performed, to date, have not proven any geriatric-specific problems that would limit the Simvastatin effectiveness in the elderly. Elderly patients should know that age-related muscle problems may be more likely while taking Simvastatin, which could require caution.

Pregnancy & Breastfeeding

Stimvastatin can harm an unborn baby or cause birth defects. Do not take this medication if you are pregnant or may become pregnant. Use effective birth control to avoid pregnancy while you are taking this medication. Simvastatin can pass into breast mile and cause harmful effects on an infant. Do not breast-feed while you are taking Simvastatin.

Other Medical Issues

To make sure Simvastatin is safe for you, tell your doctor if you have:

  • History of liver disease;
  • History of kidney disease;
  • Diabetes;
  • A thyroid disorder; or
  • If you drink more than 2 alcoholic beverages daily.

Instructions for use:

Use Simvastatin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Simvastatin is taken by mouth with or without food. Simvastatin is preferably taken in the evening unless advised otherwise by your doctor.
  • Avoid large amounts of grapefruit juice or grapefruit while taking Simvastatin (no more than 1 quart daily) as grapefruit juice may increase the amount of Simvastatin in your blood, thus increasing the risk of serious side effects. Talk to your doctor or pharmacist before including grapefruit or grapefruit juice in your diet while taking Simvastatin.
  • Do not miss any doses. Be sure to continue taking Simvastatin, even if you feel well.
  • If you miss a dose of Simvastatin, take it as soon as possible. Do not take 2 doses at once. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
  • Ask your doctor if you have any questions about how to use Simvastatin.

Simvastatin Side Effects:

Side effects can exist in all medicines, but many people have no, or minor, side effects. If any of these common side effects persist or become worrisome, be sure to discuss them with your doctor.

Common Simvastatin Side Effects

  • Heartburn
  • Gas
  • Bloating
  • Stomach pain
  • Indigestion
  • Constipation
  • Diarrhea
  • Headache
  • Joint pain
  • Muscle pain
  • Skin rash
  • Sleep problems
  • Cold symptoms (stuffy nose, sneezing, sore throat)
Major Side Effects

Contact your doctor immediately if you experience any of these side effects when taking Simvastatin.

  • Confusion
  • Fever
  • Painful urination
  • Weight gain
  • Muscle gain
  • Weakness
  • Increased hunger or thirst
  • Jaundice (yellowing of the skin or eyes)
  • Allergic reactions
  • Atrial fibrillation
  • Muscle pain
  • Tenderness
  • Dark colored urine
  • Loss of consciousness

Simvastatin Prices:

Prices are for prescriptions for 30 tablets of 40 mg:

Simastatin: $7.20

Zocor: $235.16

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Simvastatin Drug Images:

Simvastatin 40 MG

Simvastatin 40 MG

Simvastatin 5 MG

Simvastatin 5 MG

Simvastatin 10 MG

Simvastatin 10 MG

Simvastatin 80 MG

Simvastatin 80 MG

Simvastatin Alternatives:

Ezetimibe (generic for Zetia)
Pravastatin (generic for Pravachol)
Mevacor (generic for Lovastatin)

Simvastatin Patent Information:

Generic drugs don’t require patents, only brand name drugs do. Zocor’s patent exclusivity officially expired on June 23, 2006.

Simvastatin Warnings:

When taking Simvastatin, it is important to regularly visit with your doctor. This allows your doctor to evaluate how the medicine is working.

If you take any of the following drugs do not take Simvastatin, it could greatly increase your risk of serious muscle problems.

  • Cyclosporine
  • Danazol
  • Nefazodone
  • Hepatitis C medications – boceprevir, telaprevir
  • Antibiotics – clarithromycin, erythromycin, telithromycin
  • HIV/AIDS medication – atazanavir, cobicistat, darunavir, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir.

Limit alcohol use. Using alcohol daily may increase the risk of liver problems, especially if combined with Simvastatin.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine if you have major surgery, a major injury, or you develop other serious health problems.

Never split or share your medication with anyone.

If Overdose of Simvastatin is Suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Simvastatin:

Simvastatin should be stored at room temperature, between 68 and 77 degrees F (20 to 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Simvastatin out of the reach of children and away from pets.

The information provided by LowestMed is meant for educational purposes only and is not meant to be medical advice. Please seek medical advice before starting, changing or terminating any medical treatment. Discuss all medical related decisions with your physician, before adjusting anything related to your health care.